Keiichi Ishihara Selected Research

3- (1- (4- phenoxyphenyl)- 3- (2- phenylethyl)- 1H- indol- 5- yl)propanoic acid

3/2016

ASB14780, an Orally Active Inhibitor of Group IVA Phospholipase A2, Is a Pharmacotherapeutic Candidate for Nonalcoholic Fatty Liver Disease.

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Keiichi Ishihara Research Topics

Disease

9	Inflammation (Inflammations) 01/2019 - 08/2003
4	Fibrosis (Cirrhosis) 04/2022 - 10/2012
4	Down Syndrome (Down's Syndrome) 01/2019 - 01/2017
4	Asthma (Bronchial Asthma) 01/2018 - 02/2012
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2006 - 07/2003
3	Non-alcoholic Fatty Liver Disease 01/2019 - 12/2009
3	Fatty Liver 03/2016 - 12/2009
3	Cognitive Dysfunction 07/2015 - 09/2009
3	Neoplasms (Cancer) 01/2006 - 08/2003
2	Atrophy 07/2015 - 05/2015
1	Alcoholic Fatty Liver 04/2022
1	Weight Gain 01/2019
1	Atherosclerotic Plaque (Atheroma) 01/2017
1	Heart Failure 06/2015
1	Coronary Artery Disease (Coronary Atherosclerosis) 06/2015
1	Alzheimer Disease (Alzheimer's Disease) 05/2015
1	Schizophrenia (Dementia Praecox) 04/2013
1	Hyperprolactinemia 04/2013
1	Hyperplasia 01/2013
1	Airway Remodeling 01/2013
1	Eosinophilia 02/2012
1	Prostatic Neoplasms (Prostate Cancer) 02/2012
1	Hepatocellular Carcinoma (Hepatoma) 01/2011
1	Hypertrophy 12/2009
1	ST Elevation Myocardial Infarction 06/2008
1	Myocardial Infarction 06/2008
1	Hyperthermia 01/2006
1	Melanoma (Melanoma, Malignant) 10/2005
1	Colorectal Neoplasms (Colorectal Cancer) 10/2005
1	Breast Neoplasms (Breast Cancer) 10/2005

Drug/Important Bio-Agent (IBA)

5	Group IV Phospholipases A2IBA 04/2022 - 10/2012
5	AntigensIBA 01/2018 - 10/2005
4	Proteins (Proteins, Gene)FDA Link 10/2012 - 08/2005
3	LipidsIBA 01/2019 - 10/2012
3	CholesterolIBA 01/2019 - 12/2009
3	InterleukinsIBA 01/2018 - 02/2012
2	Triglycerides (Triacylglycerol)IBA 01/2019 - 01/2011
2	CopperIBA 01/2019 - 01/2019
2	Interleukin-33IBA 01/2018 - 06/2015
2	Dopamine (Intropin)FDA LinkGeneric 01/2017 - 04/2013
2	Carbon Tetrachloride (Tetrachloromethane)IBA 03/2016 - 10/2012
2	Amyloid (Amyloid Fibrils)IBA 07/2015 - 05/2015
2	florbetapirIBA 07/2015 - 05/2015
2	Amyloid beta-PeptidesIBA 07/2015 - 05/2015
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2006 - 08/2003
1	picric acid (picrate)IBA 04/2022
1	LysophospholipidsIBA 01/2019
1	EicosanoidsIBA 01/2019
1	Fluorine-18IBA 01/2017
1	Serotonin (5 Hydroxytryptamine)IBA 01/2017
1	PropaneIBA 03/2016
1	PropionatesIBA 03/2016
1	SaltsIBA 03/2016
1	3- (1- (4- phenoxyphenyl)- 3- (2- phenylethyl)- 1H- indol- 5- yl)propanoic acidIBA 03/2016
1	GlucocorticoidsIBA 06/2015
1	Adenosine (Adenocard)FDA LinkGeneric 06/2015
1	Biomarkers (Surrogate Marker)IBA 05/2015
1	Antipsychotic Agents (Antipsychotics)IBA 04/2013
1	ProlactinIBA 04/2013
1	Risperidone (Risperdal Consta)FDA LinkGeneric 04/2013
1	RacloprideIBA 04/2013
1	blonanserinIBA 04/2013
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 04/2013
1	FLB 457IBA 04/2013
1	manganese(III)-tetrakis(4-benzoic acid)porphyrinIBA 01/2013
1	ManganeseIBA 01/2013
1	MetalloporphyrinsIBA 01/2013
1	PorphyrinsIBA 01/2013
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2013
1	EnzymesIBA 10/2012
1	Arachidonic Acid (Vitamin F)IBA 10/2012
1	CytokinesIBA 02/2012
1	CXC ChemokinesIBA 02/2012
1	Monoclonal AntibodiesIBA 02/2012
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 02/2012
1	ChemokinesIBA 02/2012
1	Interleukin-10 (Interleukin 10)IBA 02/2012
1	Glucose (Dextrose)FDA LinkGeneric 02/2012
1	hydroxide ionIBA 02/2012
1	Methionine (L-Methionine)FDA Link 02/2012
1	Linoleic Acid (Linoleate)IBA 01/2011
1	Nonesterified Fatty Acids (NEFA)IBA 01/2011
1	Oleic Acid (Oleate)IBA 01/2011
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2011
1	ProstaglandinsIBA 12/2009
1	Transaminases (Aminotransferases)IBA 12/2009
1	Phospholipases (Phospholipase)IBA 12/2009
1	AcidsIBA 06/2008
1	thallium chloride (thallous chloride)IBA 06/2008
1	Troponin T (Troponin T1)IBA 06/2008
1	MB Form Creatine KinaseIBA 06/2008
1	arctigeninIBA 01/2006
1	DNA VaccinesIBA 10/2005
1	Neoplasm Antigens (Tumor Antigens)IBA 10/2005
1	DNA (Deoxyribonucleic Acid)IBA 10/2005
1	A-Form DNA (A-DNA)IBA 10/2005

Therapy/Procedure

2	Therapeutics 01/2017 - 01/2006
2	Drug Therapy (Chemotherapy) 01/2013 - 02/2012
1	Activities of Daily Living (ADL) 07/2015
1	Immunotherapy 10/2005